I agree with don't overvalue them. At the same time, I've used negs to mild remarks with lackluster effect:
A) Do you wear glasses a lot? [Response] Keep them. They make your eyes standout.
B) 1. Are you like Ms. Fashion? 2. You're wearing a sweater in here. lol What's up with that?
They'll talk for a minute. They might say thanks to the glasses compliment but it might as well be banter.
Now, I go neg when they're not responsive and I couldn't give a shi*.