Ok this was a big thing for me when starting out because getting girls at work is really easy for me. I think it's easy in general, but I see alot of guys asking about this so maybe my initial impression was wrong. Not sure, so I'm just going to say my thoughts about it.
You prob want a better answer, but it basically goes like this... It can be VERY good or VERY bad. There is no in between as far as this topic is concerned. It's basically a Mindset you must have. Getting a girl from work will be awesome or horrible. If she is not captivating you and being awesome, don't do it.
When you think like this, you can see things a little clearer. You can weed out who is not worth your time and who can be great. BUT BUT BUT... The main criteria you must hold above all else is TRUST. You can get with a girl at work as long as she is super trustworthy. If you do not allow this to be your number one qualification, you will end up bad. Very bad. We are talking about your livelihood here, so you must be extra on guard not to do anything that may jeopardize your career. That must be paramount. You must be able to trust her.
The second thing you must keep in mind is to spread yourself around with BOTH sexes. Make sure you do not single out hot women too much. Always act cool around guys as well as girls. Game girls you aren't particularly attracted to. Really try to engage guys at work, become cool with them. The purpose is to be like a juggler. People will see you in male social groups, female, ugly girls etc... You're juggling all of them. Because you do, no one can say that you single out a particular group. So if anyone makes accusations (whether actual or just perceived in their mind) there will be evidence on your side that you are simply a social guy. If your stuck up female supervisor thinks you flirt with her hot workers, she may try to say you're giving bad attention to them. BUT if you are just social, she must think about it because there us evidence that you are just a cool person who is social to all people. And because you are social, people can back you up or defend you. So alot of problems will be diffused before they even start.
The other main thing to keep in mind is that work girls are NOT your main PU targets. Alot of AFC use work as a time to hardcore game. False. News gets around quick. Once your rep is player or flirt, you may very well be sunk. So game girls at work but do not treat them as serious. Girls at work will always be a work in progress. This can be super hard because you and work girls spend alot of time together. So they will see a pretty good pix of who you are and feelings can escalate quickly (which is why AFC become "work players"). But you have to go back to what I said... Trust is number one. Even if she has a sexy butt in her tight skirt lol
So you have to take time to see who will not spread your business all over. Most girls have a girlfriend at work, so you must take note of how her best friend is also. There will always be some transmission of info... That unavoidable. But if you are awesome to her friends as well as her, there will be little damage done to your rep.
However long it is to build trust will influence how long this will take. It could be a month of working next to her or four months of seeing her once a week. Depends. If you feel you can trust her, then start with small work day date things... Going to get ice cream at lunch for example. Build up the time together alone slowly. If she brings a friend, don't be discouraged. Do the thing, and try again in a couple weeks to go with her alone. If that goes ok and she hasn't blabber it to every workmate, progress a little more. Tell her this cool thing you are going to see on the weekend. Ask her if she's seen it. Tell her she should come.
And if she proves to be untrustworthy, you can bail anytime along this process and escape relatively unharmed. But the key is building slowly and always qualify her trustworthiness.