4 basic hormones that make pickup happen. Google them if you doubt the data.
Cortisol (men and women): Keep that hormone in the woman at a minimum level. It causes stress and bad mood, and she will associate that with the guy who caused it. Also that hormone causes an unstable mood in both men and women which will screw the game. You know that cold feeling you get when you're scared. That's cortisol flowing. Cortisol also keeps pleasure hormones from making their effect.
Adrenaline (men and women): depends on the women, but if she's a teaser, almost hyper-active or a social butterfly, adrenaline can amplify emotional connection to the partner and the risky episodes they've been into. Thats why certain girls like cheating, or guys cheating their girlfriends with them and like risky moments.
Testosterone (men): try to boost this hormone to the limit. This is the hormone that gives an objective, the attention focus and the self-esteem to create a relationship with a girl. It also feeds you with sexual energy. That's why low self-esteem is a good humor destroyer and a sexual energy killer. This hormone can be raised by physical efforts, victory, happiness and good hours of sleep. Having a good Mindset and self-esteem helps testosterone production and helps a man feel more active and happy. It also makes benefits in terms of physical health.
*Stress produces cortisol, and this hormone blocks the testosterone from making its effects.
*Asma patients who take cortisone will also have development problems because cortisone also kills testosterone effects
Oxytocin (women): the famously called "the love hormone". This hormone makes the emotional connection of a woman shoot through the roof. Its released in bigger amounts in the morning and during sex. This one is the key for a girls love. It's a hormone that works like a drug. When a woman is closed to a man she loves, this hormone rises. But when his love is distant or in conflict with this woman, this hormone gets down, and as a drug, the girl feels a "hangover" which makes her miss that man. To refill the high oxytocin values, the woman needs to be with someone that makes her happy, that rises her oxytocin levels: her love, or a third person.
*We should note here that some relations and some pickup games sometimes end in nothing for no reason because there are no sufficient risks of abandonment by the man's part (Push-Pull, getting mad and not responding are examples of those risks). This lack of risks makes no strong difference in the values of this hormone but only a line of oxitocin levels getting down slowly. Till it's too late